Here is E-GUIDES of Antibiotics, Biodetergents, Stem Cell, etc. ▼
Ansamycins is a family of secondary metabolites that show antimicrobial activity against many gram-positive and some gram-negative bacteria and includes various compounds, among which: streptovaricins and rifamycins. In addition, these compounds demonstrate antiviral activity towards bacteriophages and poxviruses.
In Greek, “angio” means vessels and “genesis” is birth. Blocking angiogenesis enables us to undercut cancer’s spread. Angiogenesis is the process our bodies use to grow new bloods vessels. Cancers can hijack this process to recruit their own private blood supply to feed themselves. Without these lifelines, cancers remain tiny and can’t become dangerous. Many foods and beverages contain natural cancer-starving molecules that prevent tumors from acquiring blood vessels.
Withaferin A (WA) is derived from the medical plant Withania somnifera (commonly known as ashwagandha or Indian winter cherry), which has been safely used for centuries in Indian Ayurvedic medicine for treatment of different ailments. Suppresion of angiogenisis, alteration of cytoskeletal architecture, and inhibition of proteasomal activity by WA has also been documented.
Hypoxia-inducible factor-1 (HIF-1) is a transcriptional complex that is activated in response to hypoxia and growth factors. HIF-1 plays a central role in tumor progression, invasion, and metastasis. Overexpression of the HIF-1α subunit has been observed in many human cancers and is associated with a poor prognostic outcome with conventional treatments. Targeting HIF-1 using novel small molecule inhibitors is, therefore, an attractive strategy for therapeutic development.
Blood vessels, literally the lifelines in our bodies, are essential to delivering the nutrients our organs need to survive. A term commonly referred to as angiogenesis. But angiogenesis also has a deadly side effect: they can also feed cancerous growths.
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